Endocrine Abstracts

Objective: To evaluate the relation of mean platelet volume (MPV) levels with serum paraoxonase-1 activity in diabetic patients with respect to obesity and diabetic complications.Methods: A total of 201 diabetic patients grouped with respect to obesity obese (n=89) and non-obese (n=112) and diabetic complications with (n=50) or without (n=150) microvascular complications and with (n=91) or without (n=...

Preoperative preparation of the hyperthyroid patient for thyroidectomy is imperative to avoid perioperative complications due to severe thyrotoxicosis. 24-years old woman was admitted at our clinic for uncontrolled Graves’ disease. In our case, agranulocytosis introduced by propylthiouracil. Therefore, surgery was the only chance of an effective therapy. In cases when the patient is unresponsive to medical therapy or when such therapy is contraindicated, therapeutic plasm...

Introduction: Increased mean platelet volume (MPV) is an independent risk factor for thromboembolism, stroke and myocardial infarction. In this study we tried to emphasize the importance of gender difference in evaluation of relationship between MPV and serum biochemical parameters in type 2 diabetic patients.Methods: A total of 509 patients with diabetes mellitus who hospitalized due to several causes were retrospectively evaluated. Age, gender, other c...

Introduction: Rhabdomyolysis is usually attributed to trauma. However, there is an association of rhabdomyolysis with hyperosmolar states. It is also important to realize that hyperosmolar coma can be the presenting complaint of a diabetic seeking medical attention for the first time. In this case-report we aimed to present a patient with acute kidney injury due to rhabdomyolysis and hyperosmolar state.Case report: Forty nine-year-old black male patient ...

Introduction: Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) belongs to TNF family and is released from inflammatory cells. It has been reported that TWEAK has several biological actions ranging from cell proliferation to stimulation of apoptosis. In in vitro studies, it was reported that TWEAK has alleviating effect on insulin resistance in hepatocytes. TWEAK decreases insulin resistance induced by TNF-a through activation of phosphatase 2A pathway in a...

Aim: We aimed to evaluate wrist and ankle measurements in patients with and without diabetes-related macrovascular disease.Material and method: 151 consecutive patients with type 2 diabetes who came to our diabetic outpatient clinic were included. We have divided the patients into two groups. Group 1 (patients with diabetes related macrovascular complications) and group 2 (patients without diabetes related macrovascular complications). Group 1 (n</em...